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Registros recuperados: 72
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Recombinant viruses as vaccines against viral diseases BJMBR
Souza,A.P.D.; Haut,L.; Reyes-Sandoval,A.; Pinto,A.R..
Vaccine approaches to infectious diseases are widely applied and appreciated. Amongst them, vectors based on recombinant viruses have shown great promise and play an important role in the development of new vaccines. Many viruses have been investigated for their ability to express proteins from foreign pathogens and induce specific immunological responses against these antigens in vivo. Generally, gene-based vaccines can stimulate potent humoral and cellular immune responses and viral vectors might be an effective strategy for both the delivery of antigen-encoding genes and the facilitation and enhancement of antigen presentation. In order to be utilized as a vaccine carrier, the ideal viral vector should be safe and enable efficient presentation of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Vaccine; Immunity; Recombinant viruses; Viral vectors; Infectious disease.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000400004
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Review and perspectives of physiological mechanisms underlying genetically-based resistance of the Pacific oyster Crassostrea gigas to summer mortality ArchiMer
Samain, Jean-francois.
French oyster farming has been subject to severe mortalities during the summer months. Results from the research program "Morest", which ran from 2000 to 2006 and examined the possible causes of these mortalities, led to the construction of a model to explain the interaction between environmental factors, oyster physiology and different opportunistic pathogens underlying oyster summer mortality. Temperature, food, reproduction and stress were the main factors required for oyster mortality. Genetically-based resistance ("R" oysters) or susceptibility ("S" oysters) to summer mortality was revealed by divergent selection. Building on these results, a literature search was made in 2007 on the molecular origin of genetic resistance to such a complex mortality...
Tipo: Text Palavras-chave: Immunity; Antibacterial activity; Host defence; Environmental stress; Crassostrea gigas.
Ano: 2011 URL: http://archimer.ifremer.fr/doc/00051/16229/13752.pdf
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Seroconversion and seroreactivity patterns of dairy goats naturally exposed to caprine arthritis-encephalitis virus in Brazil Ciência Rural
Castro,Roberto Soares; Leite,Rômulo Cerqueira; Azevedo,Edisio Oliveira de; Resende,Maurício; Gouveia,Aurora Maria Guimarães.
A labelled avidin-biotin ELISA (lab-ELISA) using repeated serum samples of goats showed a progressive seroconversion with higher seroconversion rate at the period going from the beginning of the breeding up to the last half of lactation (35.0%), compared to that recorded at the beginning of breeding (17.8%)(p<0.05). Furthermore, the seroreactivity pattern, evaluated by a lab-ELISA standard-curve with serum samples collected at 30-40 days intervals during 12 months, was caracterized by high individual variability. No seroreversion was observed and there were higher titers in the group of animals which delivered kids and established a lactation period (n=6; mean titre=913.4 units) compared to the group of goats that failed to conceived (n=4; mean...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Goat; Caprine artrhitis-encephalitis virus; Diagnostics; Enzyme immunoassays; Immunity.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782002000400009
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Seronegativity to polio viruses among previously immunized adult candidates to solid organ transplantation BJID
Brandão,Luciana Gomes Pedro; Brasil,Pedro Emmanuel Alvarenga Americano do; Oliveira,Silas de Souza; Silva,Edson Elias da; Lopes,Guilherme Santoro.
ABSTRACT In the current effort to eliminate polio from the world, it is important to recognize and vaccinate susceptible groups, especially immunocompromised patients living in countries where attenuated polio vaccine is still used. In this report, we describe the frequency of protective antibodies in a small sample of adult SOT candidates in whom previous vaccination could be ascertained. Patients included in this report were selected among the participants of an ongoing prospective study carried out at the Reference Center for Special Immunobiologicals of the Evandro Chagas National Institute of Infectious Diseases in Rio de Janeiro, Brazil. Among the first 100 patients enrolled in this study, only seven adult SOT candidates had proven polio vaccination...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Poliomyelitis; Immunity; Solid organ transplantation.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000200150
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Suppression substractive hybridisation (SSH) and real time PCR reveal differential gene expression in the Pacific cupped oyster, Crassostrea gigas, challenged with Ostreid herpesvirus 1 ArchiMer
Renault, Tristan; Faury, Nicole; Barbosa Solomieu, Valérie; Moreau, Kevin.
Virus-induced genes were identified using suppression subtractive hybridisation (SSH) from Pacific cupped oyster, Crassostrea gigas, haemocytes challenged by OsHV-1. A total of 304 clones from SSH forward library were sequenced. Among these sequences, some homologues corresponded to (i) immune related genes (macrophage express protein, IK cytokine, interferon-induced protein 44 or multicopper oxidase), (ii) apoptosis related genes (Bcl-2) and (iii) cell signalling and virus receptor genes (glypican). Molecular characterization and phylogenic analysis of 3 immune-related genes (macrophage expressed protein, multicopper oxidase and immunoglobulin domain cell adhesion molecule) were performed. Finally, quantitative PCR revealed significant changes in the...
Tipo: Text Palavras-chave: Pacific cupped oyster; Crassostrea gigas; OsHV-1; Immunity; Gene expression; Multicopper oxidase; Macrophage expressed protein; Ig cell adhesion molecule; Interferon-induced protein 44; Virus RNA.
Ano: 2011 URL: http://archimer.ifremer.fr/doc/00043/15466/12843.pdf
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Susceptibility of Atta sexdens worker ants treated with the immunosuppressant Sandimmun Neoral to Metarhizium anisopliae PAB
Dornelas,Aline Silvestre Pereira; Sarmento,Renato de Almeida; Pedro-Neto,Marçal; Silva,Daniella Gonçalves da; Santos,Gil Rodrigues dos; Nascimento,Mariela Otoni do; Oliveira,Cléia Almeida; Souza,Danival José de.
Abstract: The objective of this work was to evaluate if the immunosuppressant Sandimmun Neoral enhances the activity of Metarhizium anisopliae against the leaf-cutting ant Atta sexdens. The vulnerability to the pathogen was measured by comparing the mortality rate of worker ants subjected to the following treatments: immunosuppressant+control, immunosuppressant+M. anisopliae, excipient+control, excipient+M. anisopliae, control+M. anisopliae, and control. Worker ants treated with immunosuppressant+M. anisopliae showed the highest mortality rate in comparison with those subjected to all other treatments. The use of the immunosuppressant together with entomopathogenic fungus controlled leaf-cutting ants in laboratory conditions.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biological control; Formicidae; Immunity; Immunosuppression..
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2017000200133
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The effects of a combination of garlic, oyster mushroom and propolis extract in comparison to antibiotic on growth performance, some blood parameters and nutrients digestibility of male broilers Rev. Bras. Ciênc. Avic.
Daneshmand,A; Sadeghi,GH; Karimi,A.
A study was conducted to evaluate the combined effects of garlic, oyster mushroom and propolis extract on the growth performance, organ weights, antibody response to Newcastle Disease Virus (NDV), serum lipid concentrations and nutrient digestibility of male broilers. A total of 192 day old chicks (Ross 308) were randomly assigned to 3 treatments with 4 replications (16 birds per replication). Experimental treatments were a maize- soybean based diet as control, control diet supplemented with a combination of garlic (30 g/kg), oyster mushroom (2 g/kg) and propolis extract (0.2 g/kg) known as GMP, and control diet supplemented with Virginamycin (0.25 g/kg) as antibiotic. The inclusion of GMP decreased (p < 0.05) live body weight, average daily gain and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Garlic; Mushroom; Propolis; Performance; Immunity; Broiler.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2012000200009
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The new insights into the oyster antimicrobial defense: Cellular, molecular and genetic view ArchiMer
Bachere, Evelyne; Rosa, Rafael Diego; Schmitt, Paulina; Poirier, Aurore; Merou, Nicolas; Charriere, Guillaume; Destoumieux-garzon, Delphine.
Oysters are sessile filter feeders that live in close association with abundant and diverse communities of microorganisms that form the oyster microbiota. In such an association, cellular and molecular mechanisms have evolved to maintain oyster homeostasis upon stressful conditions including infection and changing environments. We give here cellular and molecular insights into the Crassostrea gigas antimicrobial defense system with focus on antimicrobial peptides and proteins (AMPs). This review highlights the central role of the hemocytes in the modulation and control of oyster antimicrobial response. As vehicles for AMPs and other antimicrobial effectors, including reactive oxygen species (ROS), and together with epithelia, hemocytes provide the oyster...
Tipo: Text Palavras-chave: Mollusk; Immunity; Antimicrobial peptide; Hemocyte; Defensin.
Ano: 2015 URL: https://archimer.ifremer.fr/doc/00254/36552/35097.pdf
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Vaccination coverage and immunity against hepatitis B among HIV-infected patients in South Brazil BJID
Martins,Saulo; Livramento,Andréa do; Andrigueti,Michelle; Kretzer,Iara Fabricia; Machado,Marcos José; Spada,Celso; Treitinger,Arício.
Evidence-based strategies to improve the hepatitis B virus (HBV) vaccination coverage rates might help to reduce the burden caused by co-infection with HBV and human immuno-deficiency virus (HIV). In this study, the aim was to evaluate the vaccination coverage and immunity against HBV among HIV-infected individuals in South Brazil, and identify factors that are associated with compliance patterns and antibody reactivity. Three hundred HIV-infected men and women were included in this survey. The patients answered a standardized questionnaire, and vaccination cards were checked in order to assess hepatitis B vaccine status. A blood sample was collected for quantitative determination of antibody to hepatitis B virus surface antigen (anti-HBs). Participants...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV; Hepatitis B; HBV Vaccination; Immunity.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000200181
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Vaccines for finfish aquaculture: What do we need to know to make them work? Electron. J. Biotechnol.
Dixon,Brian.
Aquaculture still faces serious economic impacts due to the loss of animals to disease. A conservative estimate of 5% losses due to disease means that the finfish aquaculture industry loses over $1 billion annually on a global scale. One proven way to prevent costly disease outbreaks is to vaccinate fish against common or known pathogens. Current vaccination schemes still result in losses, however, and this may be due in part to vaccine design. Vaccines are currently designed using state of the art knowledge of immune responses, which is based primarily on mammalian studies. Just how applicable is this information to fish immunity and vaccine design, however? This review discusses what is currently known for teleost fish about two key processes that drive...
Tipo: Journal article Palavras-chave: Antibody; Antigen presentation; Cloning; Cytokine; Immunity; Major histocompatibility complex receptors.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582012000500014
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Welfare indicators for laying Japanese quails caged at different densities Anais da ABC (AABC)
SOARES,DANIELA F.; PIZZOLANTE,CARLA C.; DUARTE,KEILA MARIA R.; MORAES,JOSÉ EVANDRO DE; BUDIÑO,FÁBIO E.L.; SOARES,WEBER V.B.; KAKIMOTO,SÉRGIO K..
Abstract In the way to reduce costs in the poultry production, high densities of birds are adopted in the production systems. Such high densities can lead to an inappropriate environment, compromising the welfare and decreasing the animal performance. In this work we aimed to evaluate the effects of different densities on the productive yield, egg quality and immunological aspects of Japanese quails. It was used 816 Japanese quails, during egg production phase, in a random design, with four treatments (121.43 cm2/bird; 106.25 cm2/bird; 94.44 cm2/bird and 85.00 cm2/bird) with six repetitions each. Results indicate density did not interfere on egg quality and all treatments can be considered excellent, once the Haugh Unit was 88.03. Therefore, higher...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Immunity; IgY; Egg quality; Haugh Unit.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000703791
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การประกอบสูตรอาหารเพื่อสร้างภูมิคุ้มกันในสัตว์ Thai Agricultural
Yauvamall Kajarenl.
Tipo: Collection Palavras-chave: Nutrition; Immunity; Animal feeding; Stressors; สัตว์เศรษฐกิจ; อาหารสัตว์; โภชนาการสัตว์; ภูมิคุ้มกันโรค; สูตรอาหาร; วัตถุดิบ; ความต้องการอาหารของสัตว์; สารเสริม.
Ano: 2011 URL: http://anchan.lib.ku.ac.th/agnet/handle/001/5195
Registros recuperados: 72
Primeira ... 1234 ... Última
 

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